To Determine the Frequency of H. Pylori Infection and its Association with Lymphoid Follicle Formation in Gastritis

Authors

  • Salma Parween
  • Shafaque Mehboob
  • Binish Arif Sultan
  • Zareen Irshad
  • Asma Shaikh
  • Suresh Kumar Langhani

Abstract

Objective: To evaluate the frequency of H-pylori infection and lymphoid follicle formation in gastric biopsies.

Methodology: The presented study was a cross-sectional and performed in PNS Shifa hospital, Karachi from November 2013 to May 2014. Gastric biopsies of 122 patients of age between (15 to 65), male and female with complain of mild to severe gastritis were included, while patients on treatment or known case of carcinoma, inadequate, unfixed and crushed biopsies were excluded. Detail histopathological examination was carried out. The frequencies of H. pylori infection and lymphoid follicles formation were noticed along with the history of the patients.

Results: In the present study, out of 122 cases, 46(37.70%)were between 15-40 years of age while 76(62.30%) were in between 41-65 years of age, mean age was calculated as 44.39+12.29 years, 63(51.64%) were male and 59(48.36%) were females. Frequency of H-pylori infection and lymphoid follicles in gastric biopsies were calculated as 81(66.39%) and 49(40.16%) respectively. Significant association of H. pylori infection and lymphoid follicle formation was seen. (P-value= 0.03, by Chi-square test)

Conclusion: This study concludes that the frequency of H-pylori infection and lymphoid follicle formation (precursor of MALT lymphoma) in gastric biopsy is significantly associated and this study will help in early detection of positive cases for appropriate antibiotic therapy and H-pylori eradication therapy, thus saving the patient from developing MALT Lymphoma and other malignancies.

Keywords: H. pylori, Lymphoid follicle, MALT Lymphoma 

Downloads

Published

07-10-2020

How to Cite

1.
Parween S, Mehboob S, Sultan BA, Irshad Z, Shaikh A, Langhani SK. To Determine the Frequency of H. Pylori Infection and its Association with Lymphoid Follicle Formation in Gastritis. J Liaq Uni Med Health Sci [Internet]. 2020 Oct. 7 [cited 2024 Dec. 22];19(03):181-4. Available from: http://121.52.154.205/index.php/jlumhs/article/view/401

Issue

Vol. 19 No. 03 (2020): Journal of Liaquat University of Medical & Health Sciences

Section

Original Articles

License

Submission of a manuscript to the journal implies that all authors have read and agreed to the content of the undertaking form or the Terms and Conditions.

When an article is accepted for publication, the author(s) retain the copyright and are required to grant the publisher the right of first publication and other non-exclusive publishing rights to JLUMHS.

Articles published in the Journal of Liaquat University of Medical & health sciences are open access articles under a Creative Commons Attribution-Noncommercial - Share Alike 4.0 License. This license permits use, distribution and reproduction in any medium; provided the original work is properly cited and initial publication in this journal. This is in accordance with the BOAI definition of open access. In addition to that users are allowed to remix, tweak and build upon the work non-commercially as long as appropriate credit is given and the new creations are licensed under the identical terms. Or, in certain cases it can be stated that all articles and content there in are published under creative commons license unless stated otherwise.