COVID-19 Associated Ocular manifestation; Presented in tertiary hospital Hyderabad.
Abstract
OBJECTIVE: To explore the COVID-19 associated ocular manifestation in subjects visited tertiary
hospital Hyderabad-Pakistan.
METHODOLOGY: This observational prospective study was conducted at the Institute of
Ophthalmology, Liaquat University Medical and Health Sciences (LUMHS) Jamshoro from August 2020
to January 2021. All subjects’ ages range from 18 to 65 years visiting the out-patient eye department
and/ or admitted to the emergency ward of LUMHS Jamshoro having a positive nasopharyngeal PCR for
COVID-19 with and without ocular signs and symptoms were included. The questionnaire proforma was
designed to obtain related information. Social sciences of the statistical package, SPSS 22 version was
used for results analysis.
RESULTS: Out of one hundred and eleven subjects, forty-nine (44.1%) subjects with ocular symptoms
and Sixty-two (55.8%) without ocular symptoms had a fever and 7(14.2%) and 17(27.4%) had prior ocular
history, respectively. Conjunctival secretion (57.1%) was found the most common abnormality of ocular
surface manifestation followed by pain, redness, and burning sensation. Applying univariate analysis
general characteristics exposed that gender, age, fever, ocular prior history, ventilation mechanical,
state of disposition, and markers of inflammation were not associated significantly with ocular
symptoms.
CONCLUSION: Conjunctival secretion was found the most common abnormality of ocular surface
manifestation associated with COVID-19 infection. The increasing proportion of ocular COVID-19 signs
and symptoms cannot be ignored. To obtain better outcomes, prompt and aggressive eye management
is still necessary.
KEYWORDS: COVID 19; ocular manifestations; signs and symptoms; inflammatory markers.
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